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Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters. Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: endoribonuclease activity, cleaving siRNA-paired mRNA
Acc: GO:0070551
Aspect: Molecular Function
Desc: Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.
Synonyms:
  • argonaute endoribonuclease activity
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070551 - endoribonuclease activity, cleaving siRNA-paired mRNA (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle