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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme. The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme. The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin. The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of heme biosynthetic process
Acc: GO:0070454
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.
Synonyms:
  • negative regulation of heme anabolism
  • down regulation of heme biosynthetic process
  • negative regulation of haem biosynthetic process
  • negative regulation of heme biosynthesis
  • inhibition of heme biosynthetic process
  • negative regulation of heme formation
  • down-regulation of heme biosynthetic process
  • downregulation of heme biosynthetic process
  • negative regulation of heme synthesis
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070454 - negative regulation of heme biosynthetic process (interactive image map)
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