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Any process that modulates the frequency, rate or extent of hepatocyte differentiation. The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. Any process that stops or decreases the rate or extent of hepatocyte differentiation. Any process that activates or increases the rate or extent of hepatocyte differentiation. The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. The process whereby a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: hepatocyte differentiation
Acc: GO:0070365
Aspect: Biological Process
Desc: The process whereby a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.
Synonyms:
  • liver cell differentiation
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 15 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070365 - hepatocyte differentiation (interactive image map)
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