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Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling pathway. Any process that modulates the frequency, rate or extent of a signaling pathway. The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). Any process that stops, prevents or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. A series of reactions that occur within the cell, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of stress-activated protein kinase signaling pathway
Acc: GO:0070303
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling pathway.
Synonyms:
  • negative regulation of SAPK signaling pathway
  • negative regulation of stress-activated protein kinase signalling pathway
  • inhibition of stress-activated protein kinase signaling pathway
  • downregulation of stress-activated protein kinase signaling pathway
  • down-regulation of stress-activated protein kinase signaling pathway
  • down regulation of stress-activated protein kinase signaling pathway
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 45 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070303 - negative regulation of stress-activated protein kinase signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle