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A biological process that results in permanent cessation of all vital functions of a cell. A cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors and Toll-like receptors. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism. Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents. A cellular process that results in swelling of the cell body, and that is morphologically characteristic of necrotic cell death. Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: necrotic cell death
Acc: GO:0070265
Aspect: Biological Process
Desc: A cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.
Synonyms:
  • cellular necrosis
  • necrosis
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 23 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070265 - necrotic cell death (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle