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Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group. Catalysis of the hydrolysis of 5'-phosphotyrosyl moieties formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA. Catalysis of the hydrolysis of phosphotyrosyl moieties formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 5'-tyrosyl-DNA phosphodiesterase activity
Acc: GO:0070260
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of 5'-phosphotyrosyl moieties formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070260 - 5'-tyrosyl-DNA phosphodiesterase activity (interactive image map)
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