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Any process that modulates the occurrence or rate of T cell death by apoptosis. The process of apoptosis in a thymocyte. Any process that stops, prevents or reduces the frequency, rate or extent of T cell death by apoptosis. The process of apoptosis in a lymphocyte. The process of apoptosis in a T cell. A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. Any process that activates or increases the frequency, rate or extent of T cell death by apoptosis. A type of T cell apoptosis that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors. A type of T cell apoptosis that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: T cell apoptosis
Acc: GO:0070231
Aspect: Biological Process
Desc: The process of apoptosis in a T cell.
Synonyms:
  • T-lymphocyte apoptosis
  • programmed cell death of T cells by apoptosis
  • T-cell apoptosis
  • T lymphocyte apoptosis
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 26 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070231 - T cell apoptosis (interactive image map)
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