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The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. The process by which the neural tube is regionalized in the dorsoventral axis. The regionalization process by which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell. The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: smoothened signaling pathway involved in dorsal/ventral neural tube patterning
Acc: GO:0060831
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.
Synonyms:
  • hh signaling pathway involved in dorsal/ventral neural tube patterning
  • hedgehog signaling pathway involved in dorsal/ventral neural tube patterning
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060831 - smoothened signaling pathway involved in dorsal/ventral neural tube patterning (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle