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The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell. Complex formation involves dimerization of a receptor protein tyrosine kinase followed by the association of several different intracellular signaling molecules with the cytoplasmic tails of the receptors. Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway. Grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response. The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell. The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: ciliary receptor clustering involved in smoothened signaling pathway
Acc: GO:0060830
Aspect: Biological Process
Desc: Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.
Synonyms:
  • ciliary receptor clustering involved in hedgehog signaling pathway
  • ciliary receptor clustering involved in hh signaling pathway
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060830 - ciliary receptor clustering involved in smoothened signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle