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The formation of the ectoderm, mesoderm and endoderm during gastrulation. The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt a mesoderm fate. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in cells adopting an endoderm, ectoderm or mesoderm cell fate. The commitment of cells to specific cell fates of the endoderm, ectoderm and mesoderm as a part of gastrulation. The process by which a cell becomes committed to become part of the mesoderm. A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. The process by which a cell becomes committed to become part of the endoderm. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. The process by which a cell becomes committed to become part of the ectoderm.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cell fate commitment involved in the formation of primary germ layers
Acc: GO:0060795
Aspect: Biological Process
Desc: The commitment of cells to specific cell fates of the endoderm, ectoderm and mesoderm as a part of gastrulation.
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 81 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060795 - cell fate commitment involved in the formation of primary germ layers (interactive image map)
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