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The process whereby an activated receptor conveys information down the signaling pathway, resulting in a change in the function or state of a cell. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. The process whereby a signal is released and/or conveyed from one location to another. The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: SMAD protein signal transduction
Acc: GO:0060395
Aspect: Biological Process
Desc: The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.
Proteins in PDR annotated with:
   This term: 46 [Search]
   Term or descendants: 46 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060395 - SMAD protein signal transduction (interactive image map)
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