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The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state. A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle. A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mesenchymal to epithelial transition
Acc: GO:0060231
Aspect: Biological Process
Desc: A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.
Synonyms:
  • mesenchymal-epithelial transition
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 20 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060231 - mesenchymal to epithelial transition (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle