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Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. The binding activity of a molecule that brings together a molecule of the JAK signal transduction pathway and one or more other molecules of the pathway, permitting them to function in a coordinated way. The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68). The binding activity of a molecule that brings together two or more molecules, permitting those molecules to function in a coordinated way. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria. The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other molecules, permitting them to function in a coordinated way. The binding activity of a molecule that brings together a transmembrane receptor protein kinase and one or more other molecules, permitting them to function in a coordinated way. The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way. The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis. The binding activity of a molecule that brings together a cytoskeletal molecule and one or more other molecules, permitting them to function in a coordinated way.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: molecular adaptor activity
Acc: GO:0060090
Aspect: Molecular Function
Desc: The binding activity of a molecule that brings together two or more molecules, permitting those molecules to function in a coordinated way.
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 83 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060090 - molecular adaptor activity (interactive image map)
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Created and Maintained by: Michael Riffle