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The directed movement of acetylcholine into, out of, within or between cells by means of some external agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. Any process that prevents the activation of the directed movement of acetylcholine into a cell. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. It does not occur during cholinergic synaptic transmission. Instead, acetylcholine is enzymatically degraded in the synaptic cleft. The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of amines into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell. Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell. The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of acetylcholine uptake
Acc: GO:0051632
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell.
Synonyms:
  • down-regulation of acetylcholine uptake
  • downregulation of acetylcholine uptake
  • negative regulation of acetylcholine import
  • down regulation of acetylcholine uptake
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051632 - negative regulation of acetylcholine uptake (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle