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Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Any process that modulates the activity of an enzyme. Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate. Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. Any process that activates, maintains or increases the rate of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. Any process that activates or increases the activity of an enzyme.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: positive regulation of ligase activity
Acc: GO:0051351
Aspect: Biological Process
Desc: Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
Synonyms:
  • ligase activator
  • stimulation of ligase activity
  • upregulation of ligase activity
  • up-regulation of ligase activity
  • up regulation of ligase activity
  • activation of ligase activity
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 107 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051351 - positive regulation of ligase activity (interactive image map)
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