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Catalysis of the reaction: sirohydrochlorin + Fe2+ = siroheme + 2 H+. Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. Catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: sirohydrochlorin ferrochelatase activity
Acc: GO:0051266
Aspect: Molecular Function
Desc: Catalysis of the reaction: sirohydrochlorin + Fe2+ = siroheme + 2 H+.
Synonyms:
  • siroheme ferro-lyase (sirohydrochlorin-forming)
  • SirB
  • Met8P
  • CysG
  • sirohydrochlorin ferro-lyase activity
  • siroheme synthase activity
Proteins in PDR annotated with:
   This term: 5 [Search]
   Term or descendants: 5 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051266 - sirohydrochlorin ferrochelatase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle