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Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). Any process that stops, prevents or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. Any process that stops, prevents or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds. The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of membrane protein ectodomain proteolysis
Acc: GO:0051045
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.
Synonyms:
  • down regulation of membrane protein ectodomain proteolysis
  • downregulation of membrane protein ectodomain proteolysis
  • down-regulation of membrane protein ectodomain proteolysis
  • inhibition of membrane protein ectodomain proteolysis
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051045 - negative regulation of membrane protein ectodomain proteolysis (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle