YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

The process whereby phagocytes engulf external particulate material. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. Any process that modulates the frequency, rate or extent of phagocytosis, the process whereby phagocytes engulf external particulate material. Any process that stops, prevents or reduces the frequency, rate or extent of phagocytosis. Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Any process that modulates the frequency, rate or extent of endocytosis. Any process that stops, prevents or reduces the frequency, rate or extent of endocytosis. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore. A type of vesicle-mediated transport in which cells take up external materials or membrane constituents by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of phagocytosis
Acc: GO:0050765
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of phagocytosis.
Synonyms:
  • downregulation of phagocytosis
  • down-regulation of phagocytosis
  • inhibition of phagocytosis
  • down regulation of phagocytosis
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 10 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050765 - negative regulation of phagocytosis (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle