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The regulated release of interleukin-1 from a cell or group of cells. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation by inducing interleukin 2 release and it is involved in the inflammatory response. Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 from a cell or group of cells. Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production. The regulated release of interleukin 1 beta from a cell or group of cells. Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production. The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell or group of cells. Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of cytokines from a cell or group of cells. Any process that modulates the frequency, rate, or extent of interleukin-1 beta production. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of interleukin-1 from a cell or group of cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of interleukin-1 beta secretion
Acc: GO:0050713
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell or group of cells.
Synonyms:
  • down regulation of interleukin-1 beta secretion
  • down-regulation of interleukin-1 beta secretion
  • inhibition of interleukin-1 beta secretion
  • downregulation of interleukin-1 beta secretion
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050713 - negative regulation of interleukin-1 beta secretion (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle