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The regulated release of cytokines from a cell or group of cells. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. The controlled release of proteins from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of cytokines from a cell or group of cells. The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that modulates the frequency, rate, or extent of production of a cytokine. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of interleukin-1 from a cell or group of cells. Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine secretion during immune response. Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta secretion. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells. Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell or group of cells. Any process that modulates the frequency, rate or extent of the regulated release of cytokines from a cell or group of cells. Any process that decreases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell or group of cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of cytokine secretion
Acc: GO:0050710
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of cytokines from a cell or group of cells.
Synonyms:
  • down regulation of cytokine secretion
  • inhibition of cytokine secretion
  • down-regulation of cytokine secretion
  • downregulation of cytokine secretion
Proteins in PDR annotated with:
   This term: 10 [Search]
   Term or descendants: 14 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050710 - negative regulation of cytokine secretion (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle