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The controlled release of proteins from a cell or group of cells. Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a substance from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of cytokines from a cell or group of cells. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore. The directed movement of proteins into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. The controlled release of a substance by a cell, a group of cells, or a tissue. Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore. Any process that stops, prevents or reduces the frequency, rate or extent of the regulated release of immunoglobulins from a cell or group of cells. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells. Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell or group of cells. The controlled release of a substance by a cell. Any process that modulates the frequency, rate or extent of a process by which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells by means of some external agent such as a transporter or pore.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of protein secretion
Acc: GO:0050709
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of a protein from a cell or group of cells.
Synonyms:
  • down regulation of protein secretion
  • down-regulation of protein secretion
  • inhibition of protein secretion
  • downregulation of protein secretion
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 22 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0050709 - negative regulation of protein secretion (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle