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Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ = (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 15-oxoprostaglandin 13-oxidase activity
Acc: GO:0047522
Aspect: Molecular Function
Desc: Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ = (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+.
Synonyms:
  • 15-oxoprostaglandin 13-reductase activity
  • prostaglandin delta13-reductase activity
  • 15-oxo-delta13-prostaglandin reductase activity
  • (5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta13-oxidoreductase activity
  • prostaglandin 13-reductase activity
  • delta13-15-ketoprostaglandin reductase activity
  • 15-ketoprostaglandin delta13-reductase activity
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0047522 - 15-oxoprostaglandin 13-oxidase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle