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Any process that modulates the frequency, rate or extent of mitosis. Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle. The cell cycle process whereby centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle. Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis. Any process that stops, prevents or reduces the frequency, rate or extent of centrosome separation. Any process that activates or increases the frequency, rate or extent of centrosome separation. Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation. Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. Any process that modulates the rate or extent of progress through the mitotic cell cycle. A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. The process by which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle. Any process that modulates the rate or extent of progression through the cell cycle. Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of mitotic centrosome separation
Acc: GO:0046602
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis.
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0046602 - regulation of mitotic centrosome separation (interactive image map)
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