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A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. Any process that modulates the frequency, rate or extent of chromosome segregation, the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Any process that stops, prevents or reduces the frequency, rate or extent of sister chromatid cohesion. Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained. Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. The process by which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Any process that stops, prevents or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. The cell cycle process by which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome. Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. Any process that modulates the frequency, rate or extent of sister chromatid cohesion. Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of sister chromatid cohesion
Acc: GO:0045875
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of sister chromatid cohesion.
Synonyms:
  • down regulation of sister chromatid cohesion
  • down-regulation of sister chromatid cohesion
  • downregulation of sister chromatid cohesion
  • inhibition of sister chromatid cohesion
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045875 - negative regulation of sister chromatid cohesion (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle