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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. Any process that stops, prevents or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. Any process that stops, prevents or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. Any process that stops, prevents or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds. The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification. The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of proteolysis
Acc: GO:0045861
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:
  • down regulation of proteolysis
  • down-regulation of proteolysis
  • negative regulation of peptidolysis
  • downregulation of proteolysis
  • inhibition of proteolysis
Proteins in PDR annotated with:
   This term: 63 [Search]
   Term or descendants: 79 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045861 - negative regulation of proteolysis (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle