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Any process that modulates the frequency, rate or extent of osteoblast differentiation. Any process that modulates the frequency, rate or extent of bone formation. Any process that stops, prevents or reduces the frequency, rate or extent of osteoblast differentiation. The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates the frequency, rate or extent of cell differentiation, the process whereby relatively unspecialized cells acquire specialized structural and functional features. Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation. The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, the mesodermal cell that gives rise to bone.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of osteoblast differentiation
Acc: GO:0045668
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of osteoblast differentiation.
Synonyms:
  • downregulation of osteoblast differentiation
  • inhibition of osteoblast differentiation
  • down regulation of osteoblast differentiation
  • down-regulation of osteoblast differentiation
Proteins in PDR annotated with:
   This term: 24 [Search]
   Term or descendants: 24 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045668 - negative regulation of osteoblast differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle