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The process whereby a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. Any process that stops, prevents or reduces the frequency, rate or extent of myeloid cell differentiation. The process whereby a relatively unspecialized monocyte acquires the specialized features of a macrophage. Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. Any process that modulates the frequency, rate or extent of macrophage differentiation. Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of macrophage differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of macrophage differentiation
Acc: GO:0045650
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of macrophage differentiation.
Synonyms:
  • downregulation of macrophage differentiation
  • down-regulation of macrophage differentiation
  • inhibition of macrophage differentiation
  • down regulation of macrophage differentiation
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045650 - negative regulation of macrophage differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle