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The cellular metabolic process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair. The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity. Any process that prevents the collapse of stalled replication forks. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. Any cellular metabolic process involving nucleic acids. A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication. The process by which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted. Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: maintenance of fidelity involved in DNA-dependent DNA replication
Acc: GO:0045005
Aspect: Biological Process
Desc: A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair.
Synonyms:
  • maintenance of fidelity during DNA-dependent DNA replication
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 51 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045005 - maintenance of fidelity involved in DNA-dependent DNA replication (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle