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The chemical reactions and pathways involving aflatoxins with a B designation. Distinguished from other aflatoxins by their exhibition of blue fluorescence under UV light. The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450. The chemical reactions and pathways involving aflatoxin B1, a potent hepatotoxic and hepatocarcinogenic mycotoxin produced by various species from the Aspergillus group of fungi.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: aflatoxin B1 metabolic process
Acc: GO:0043390
Aspect: Biological Process
Desc: The chemical reactions and pathways involving aflatoxin B1, a potent hepatotoxic and hepatocarcinogenic mycotoxin produced by various species from the Aspergillus group of fungi.
Synonyms:
  • aflatoxin B1 metabolism
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043390 - aflatoxin B1 metabolic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle