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Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation. Any process that stops, prevents, or reduces the rate of natural killer cell degranulation. Any process that modulates the frequency, rate, or extent of natural killer cell degranulation. The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell. The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines. A process that directly activates any of the steps required for cell death by apoptosis. The regulated exocytosis of secretory granules by a leukocyte. The directed killing of a target cell by a leukocyte. A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. Any process of the immune system that occurs as part of an immune response. The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: natural killer cell degranulation
Acc: GO:0043320
Aspect: Biological Process
Desc: The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell.
Synonyms:
  • natural killer cell granule exocytosis
  • NK cell degranulation
  • NK cell granule exocytosis
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043320 - natural killer cell degranulation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle