YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that decreases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. Any process that modulates the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. A series of reactions initiated by the activation of the transcription factor NF-kappaB. NF-kappaB is sequestered by the inhibitor I-kappaB, and is released when I-kappaB is phosphorylated by activated I-kappaB kinase. Any process that modulates an I-kappaB kinase/NF-kappaB induced cascade. A series of reactions that occur within the cell, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. Any process that stops, prevents or reduces the frequency, rate or extent of an I-kappaB kinase/NF-kappaB induced cascade.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of I-kappaB kinase/NF-kappaB cascade
Acc: GO:0043124
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of an I-kappaB kinase/NF-kappaB induced cascade.
Synonyms:
  • downregulation of I-kappaB kinase/NF-kappaB cascade
  • inhibition of I-kappaB kinase/NF-kappaB cascade
  • down-regulation of I-kappaB kinase/NF-kappaB cascade
  • down regulation of I-kappaB kinase/NF-kappaB cascade
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 14 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043124 - negative regulation of I-kappaB kinase/NF-kappaB cascade (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle