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The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus. The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. A type of T cell apoptosis that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors. A type of T cell apoptosis that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products. The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: T cell homeostasis
Acc: GO:0043029
Aspect: Biological Process
Desc: The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
Synonyms:
  • T-cell homeostasis
  • T-lymphocyte homeostasis
  • T lymphocyte homeostasis
Proteins in PDR annotated with:
   This term: 21 [Search]
   Term or descendants: 35 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043029 - T cell homeostasis (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle