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Any process that stops, prevents or reduces the frequency, rate or extent of the transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane. Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. Any process that stops, prevents or reduces the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus. Any process that stops, prevents or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus. Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus. The directed movement of a protein from the cytoplasm to the nucleus. Any process that stops, prevents or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus. The directed movement of a transcription factor from the cytoplasm to the nucleus.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of transcription factor import into nucleus
Acc: GO:0042992
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.
Synonyms:
  • negative regulation of transcription factor import into cell nucleus
  • negative regulation of transcription factor-nucleus import
  • down regulation of transcription factor import into nucleus
  • downregulation of transcription factor import into nucleus
  • inhibition of transcription factor import into nucleus
  • negative regulation of transcription factor transport from cytoplasm to nucleus
  • down-regulation of transcription factor import into nucleus
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 22 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042992 - negative regulation of transcription factor import into nucleus (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle