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The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. Any process that modulates the frequency, rate or extent of B cell activation. A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. Any process that stops, prevents or reduces the frequency, rate or extent of B cell activation. The expansion of a B cell population by cell division. Follows B cell activation. The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus. Any process that activates or increases the frequency, rate or extent of B cell activation. The process whereby a precursor cell type acquires the specialized features of a B cell. The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell. The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: B cell activation
Acc: GO:0042113
Aspect: Biological Process
Desc: The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Synonyms:
  • B lymphocyte activation
  • B-lymphocyte activation
  • B-cell activation
Proteins in PDR annotated with:
   This term: 37 [Search]
   Term or descendants: 200 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0042113 - B cell activation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle