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Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. Formation of a multilayered, melanized sheath of cells around a foreign invader. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. Any process that affects the rate, extent or location of the melanization defense response during injury or invasion. The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin. Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom. Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection. Any process that increases the rate or extent of the melanization defense response during injury or invasion. The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: melanization defense response
Acc: GO:0035006
Aspect: Biological Process
Desc: The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.
Synonyms:
  • melanization defence response
Proteins in PDR annotated with:
   This term: 10 [Search]
   Term or descendants: 11 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0035006 - melanization defense response (interactive image map)
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