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Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate. Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate. Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate. Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidyl inositol-4-phosphate + phosphate. Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol. Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate. Catalysis of the removal of one of the two phosphate groups of a phosphatidylinositol bisphosphate. Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: phosphatidylinositol bisphosphate phosphatase activity
Acc: GO:0034593
Aspect: Molecular Function
Desc: Catalysis of the removal of one of the two phosphate groups of a phosphatidylinositol bisphosphate.
Synonyms:
  • phosphatidylinositol-bisphosphatase activity
  • phosphatidyl-inositol-bisphosphate phosphatase activity
  • triphosphoinositide phosphatase activity
  • diphosphoinositide phosphatase activity
  • triphosphoinositide phosphomonoesterase activity
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 49 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0034593 - phosphatidylinositol bisphosphate phosphatase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle