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Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate. Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. Any process that stops or reduces the rate of activity of a GTPase of the Ras superfamily. Any process that stops or reduces the activity of an enzyme. Any process that modulates the rate of GTP hydrolysis by a GTPase. Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of GTPase activity
Acc: GO:0034260
Aspect: Biological Process
Desc: Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
Synonyms:
  • inhibition of GTPase activity
  • down regulation of GTPase activity
  • negative regulation of guanosinetriphosphatase activity
  • down-regulation of GTPase activity
  • downregulation of GTPase activity
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0034260 - negative regulation of GTPase activity (interactive image map)
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Created and Maintained by: Michael Riffle