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Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway. Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway. Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway. Any series of molecular signals generated as a consequence of binding to a cell surface or intracellular pattern recognition receptor (PRR). Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens. Any series of molecular signals generated as a consequence of binding to toll-like receptor 4. Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: toll-like receptor 4 signaling pathway
Acc: GO:0034142
Aspect: Biological Process
Desc: Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.
Synonyms:
  • TLR4 signaling pathway
  • toll-like receptor 4 signalling pathway
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0034142 - toll-like receptor 4 signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle