YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor. Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = (24S)-24-hydroxycholesterol + NADP+ + H2O. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: cholesterol 24-hydroxylase activity
Acc: GO:0033781
Aspect: Molecular Function
Desc: Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = (24S)-24-hydroxycholesterol + NADP+ + H2O.
Synonyms:
  • cholesterol 24-monooxygenase activity
  • CYP46
  • cytochrome P450 46A1
  • cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity
  • CYP46A1
  • cholesterol 24S-hydroxylase activity
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0033781 - cholesterol 24-hydroxylase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle