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Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid. Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule. Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase activity. Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule. Any process that stops or reduces the activity of an enzyme. Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of kinase activity
Acc: GO:0033673
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
Synonyms:
  • kinase inhibitor
  • down regulation of kinase activity
  • down-regulation of kinase activity
  • downregulation of kinase activity
  • inhibition of kinase activity
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 213 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0033673 - negative regulation of kinase activity (interactive image map)
YRC Informatics Platform - Version 3.0
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