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The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain. The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds. The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: membrane protein proteolysis
Acc: GO:0033619
Aspect: Biological Process
Desc: The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 50 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0033619 - membrane protein proteolysis (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle