| Desc: |
A series of molecular signals that results in activation of transcription by a member of the NFAT protein family as a consequence of NFAT dephosphorylation by activated calcineurin. The signaling is generated by a receptor binding a ligand, followed by activation of phospholipase C and the subsequent release of inositol trisphosphate, which in turn leads to an increase in intracellular calcium ion concentration that mediates the activation of calcineurin. |
