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The process whereby a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus. The process by which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation in the thymus. Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation. Any process that modulates the frequency, rate or extent of T cell differentiation. Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation. Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus. Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte differentiation.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of T cell differentiation in the thymus
Acc: GO:0033085
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation in the thymus.
Synonyms:
  • negative regulation of thymocyte cell differentiation
  • negative regulation of thymocyte differentiation
  • negative regulation of thymic T cell differentiation
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0033085 - negative regulation of T cell differentiation in the thymus (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle