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The morphological and physiological alterations undergone by mitochondria during apoptosis. The process by which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol. A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: release of matrix enzymes from mitochondria
Acc: GO:0032976
Aspect: Biological Process
Desc: The process by which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
Synonyms:
  • mAST release from mitochondria
  • release of aspartate aminotransferase from mitochondria
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032976 - release of matrix enzymes from mitochondria (interactive image map)
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Created and Maintained by: Michael Riffle