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The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Any process that modulates the frequency, rate, or extent of tumor necrosis factor production. Any process that stops, prevents or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production. Any process that stops, prevents, or reduces the rate of production of a cytokine. The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Any process that modulates the frequency, rate, or extent of production of a cytokine.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of tumor necrosis factor production
Acc: GO:0032720
Aspect: Biological Process
Desc: Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
Synonyms:
  • negative regulation TNF-alpha production
  • inhibition of tumor necrosis factor production
  • down regulation of tumor necrosis factor production
  • negative regulation tumor necrosis factor-alpha production
  • downregulation of tumor necrosis factor production
  • down-regulation of tumor necrosis factor production
  • negative regulation TNF production
Proteins in PDR annotated with:
   This term: 30 [Search]
   Term or descendants: 30 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032720 - negative regulation of tumor necrosis factor production (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle