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A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication. The process by which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases. The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage. The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: DNA duplex unwinding
Acc: GO:0032508
Aspect: Biological Process
Desc: The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
Synonyms:
  • duplex DNA melting
  • DNA unwinding
Proteins in PDR annotated with:
   This term: 13 [Search]
   Term or descendants: 115 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032508 - DNA duplex unwinding (interactive image map)
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