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Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA. Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents, or reduces the frequency, rate, or extent of a homeostatic process. The cellular metabolic process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase. Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and the length of telomeric DNA. These processes includes those that shorten and lengthen the telomeric DNA sequences. Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. Any process that stops, prevents or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication. The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase. The process whereby new strands of DNA are synthesized, using RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. Any process that modulates the frequency, rate or extent of DNA replication.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of telomere maintenance via telomerase
Acc: GO:0032211
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.
Synonyms:
  • down-regulation of telomere maintenance via telomerase activity
  • down regulation of telomere maintenance via telomerase activity
  • downregulation of telomere maintenance via telomerase activity
  • inhibition of telomere maintenance via telomerase
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 8 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032211 - negative regulation of telomere maintenance via telomerase (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle