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Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids. Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA. Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. Any process that stops or reduces the activity of an enzyme. Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of nuclease activity
Acc: GO:0032074
Aspect: Biological Process
Desc: Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
Synonyms:
  • inhibition of nuclease activity
  • down regulation of nuclease activity
  • nuclease inhibitor
  • down-regulation of nuclease activity
  • downregulation of nuclease activity
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032074 - negative regulation of nuclease activity (interactive image map)
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