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Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription. Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. The process leading to expression of genes that are typically not expressed due to silencing by regulatory proteins. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any process that decreases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin. The cellular synthesis of RNA on a template of DNA. Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. Any cellular process that activates or increases the frequency, rate or extent of transcription. Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any epigenetic process that stops, prevents or reduces the rate of gene expression. Any epigenetic process that activates or increases the rate of gene expression. Any process that affects the rate, extent or location of chromatin silencing. Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. Any process that stops, prevents or reduces the frequency, rate or extent of chromatin silencing at telomeres. Any process that activates or increases the frequency, rate or extent of cellular DNA-dependent transcription. Any process that stops, prevents or reduces the frequency, rate or extent of cellular DNA-dependent transcription. Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. Any process that decreases the frequency, rate or extent of chromatin silencing by small RNA. Chromatin silencing by small RNA is the repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region. Any process that stops, prevents or reduces the frequency, rate or extent of chromatin silencing.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of chromatin silencing
Acc: GO:0031936
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of chromatin silencing.
Synonyms:
  • negative regulation of heterochromatic silencing
  • down-regulation of chromatin silencing
  • downregulation of chromatin silencing
  • inhibition of chromatin silencing
  • down regulation of chromatin silencing
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 24 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031936 - negative regulation of chromatin silencing (interactive image map)
YRC Informatics Platform - Version 3.0
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