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Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Any process that modulates the frequency, rate or extent of a signaling pathway. A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria. The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. Any process that stops, prevents or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. The series of molecular signals generated in response to detection of lipopolysaccharide. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of lipopolysaccharide-mediated signaling pathway
Acc: GO:0031665
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
Synonyms:
  • down regulation of lipopolysaccharide-mediated signaling pathway
  • inhibition of lipopolysaccharide-mediated signaling pathway
  • down-regulation of lipopolysaccharide-mediated signaling pathway
  • downregulation of lipopolysaccharide-mediated signaling pathway
  • negative regulation of LPS-mediated signaling pathway
  • negative regulation of lipopolysaccharide-mediated signalling pathway
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031665 - negative regulation of lipopolysaccharide-mediated signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle